Breast
Cancer and the Environment
As Featured in SCNM
Spotlight by: Chris Spooner N.D.
After
skin cancer, breast cancer is the most common cancer in women.
Rates of breast cancer have nearly tripled in the United States
in the past 50 years. Since 1980, the incidence of breast
cancer among North American women has increased by 32 percent.
As many as 2 million women in North America were diagnosed
with breast cancer during the 1990’s.
More American
women have died of breast cancer in the past two decades than
all the Americans killed in World War I, World War II, the
Korean War and the Vietnam War combined. The average woman
killed by breast cancer loses 20 years of her life. The rates
are rising. Since 1940 there has been a continual rise of
one percent each year. Since 1940, a woman’s chance
of getting breast cancer has doubled. The lifetime risk of
a woman developing breast cancer in the 1940’s was 1
in 22. In 2002 it was 1 in 8. This relentless increase cannot
be explained by an aging population or by better detections
such as mammography screening.
This increase
is visible in the U.S., Canada, Japan, Denmark, the Nordic
countries and elsewhere in the “developed” world.
The reasons for this steady increase are not understood. On
the other hand, the death rate from breast cancer is dropping
slightly because tumors are now being found earlier.
Combinations
of factors are contributing to the gradual increase. Between
30 and 50 percent of breast cancer can be explained by genetic
inheritance or by factors in a woman’s life that increase
her exposure to natural estrogens in the blood stream. That
leaves 50 to 70% of breast cancers remain unexplained. In
theory, the current generation of women in their 50’s
should be benefiting from the protective effects of having
children earlier. Yet this generation’s incidence of
breast cancer has been steadily increasing. Clearly something
else is overwhelming these protective reproduction-related
“risk factors”.
The “something
else” is no doubt a combination of lifestyle and environmental
conditions. Consider the following: Breast cancer incidence
is five times as high in some countries as others. When women
migrate from a country with low incidence of breast cancer
to a country with high incidence, their daughters acquire
the breast-cancer risk prevailing in the high-incidence country.
Clearly, something in the environment is at work here. Research
has shown definite links between increased cancer rates and
exposure to factors such as medical irradiation, exposures
to certain chemicals, pharmaceuticals, pesticides, and food
additives. These exposures combined with lack of exercise,
and weight gain are most likely contributing to increases
in breast cancer.
When the
National Health Service was
asked about Breast Cancer over the next 30 years they stated
that it will still be incurable but it will be more of a disease
that women live with rather than die from.
While
much progress has been made of early screening and detection
with mammograms and awareness, the objective of primary prevention
should ultimately be to prevent the disease process from starting.
The role
of estrogen like compounds (xenoestrogens) in the environment
and their ability to increase the total estrogen load in a
woman’s body cannot be overstated. Total estrogen exposure
is the single most important risk factor for breast cancer,
estrogenic chemicals, which would add to their lifelong exposure,
are an obvious suspect when searching for the cause of rising
rates of breast cancer over the past half century. A study
of breast cancer risk based on estrogen levels in 15,000 women
found that women with higher estrogen levels were more likely
to go on to develop breast cancer.
Studies
show that hormone disrupting chemicals can act together and
that small, seemingly insignificant quantities of individual
chemicals can have a major cumulative effect and that multiple
estrogenic chemicals can act together to produce an effect
even when each individual component of the mixture is below
a threshold for effect.
Examples
include:
1) In
one-study women who breathed vinyl chloride fumes on the job
showed a 36% increase in breast cancer deaths.
2) A study
of 501,536 women who received the pharmaceutical diethylstilbestrol
(DES) showed a 34% increase in developing breast cancer.
3) Reportedly,
85% of pharmaceutical drugs involve chlorinated chemicals
in the manufacturing process. A 1979 study by the National
Cancer Institute revealed excessive breast cancer among
1,075 Caucasian women employed in pharmaceutical manufacture.
4) A New
Jersey Study revealed excessive breast cancer among African
American female pharmaceutical workers, chemical workers,
electrical equipment workers, and printing plant workers.
5) A New
York study of Caucasian women in the electrical equipment
and printing industries exposed to chlorinated solvents showed
elevated rates of breast cancer.
6) Women
employed as beauticians for more than five years have a three-fold
increased likelihood of getting breast cancer.
7) Breast
cancer has increased in 339 U.S. counties that have hazardous
waste sites and groundwater contamination compared to counties
without such sites. In this study of waste dumps and cancers
between 1970-1979, breast cancer was the most elevated among
women.
8) Fisherman’s
wives who ate organochlorine contaminated fish from the Baltic
Sea (east coast of Sweden), have an elevated incidence of
breast cancer compared to women eating less-contaminated fish
from the west coast FO Sweden.
9) Women
occupationally exposed to 2,4,5 Trichlorophenol the herbicide
involved with Agent Orange and Dioxin had an elevated incidence
of breast cancer.
The list
of substances that demonstrate estrogen like properties continues
to rise. Part of the problem is that the majority of the 80,000
plus compounds in our environment have not been tested for
chronic-low dose toxicity. Chemicals of particular concern
include organochlorine compounds, dioxins, cadmium, pthalates
(found in plastics, specifically heating of plastics), bisphenol
A, PCB’s and PBB’s (found in bottom dwellers such
as shellfish).
DR. PURCELL’S
COMMENTS:
It is
clear from this article that breast cancer has an environmental
component. As with many disease states one component usually
isn’t enough to tip the apple cart.
In the
afore mentioned studies perhaps the occupational exposure
to those women was enough to cause cancer since the dose makes
the poison. But in many cases today the dose of one single
event may not be the cause but the chronic low dose toxicity
over time. Breast Cancer is a complex disease, which means
that the approach weather in prevention or in treatment must
be multi-factorial.
In
terms of prevention we must limit our known environmental
exposure as much as possible:
*Simple
things such as filtering water instead of drink it bottled.
*Refusing to microwave in plastic containers.
*Eating organic produce and at the very least avoiding produce
from Mexico.
(Many of the toxic compounds at risk to humans have been banned
in the US but not in other countries that our produce is imported
from.)
*Eliminating toxic household cleaning products for safer ones.
*Reducing consumption of salmon, tuna, and swordfish to no
more than once a week.
*Avoiding the consumption of shellfish or bottom dwellers.
*Using a “green” exterminator. Remember if it
was made to kill a live organism it can also kill you.
*Refrain from putting anything on your body that you wouldn’t
put in your mouth.
*Check skin care products and make-up for toxic compounds
and xenoestrogens. (Methyl and Propyl parabins that are found
in many body products and make-up as a preservative have been
found inside breast cancer cells.
*Eating organic dairy and meats. These products have hormones
that mimic estrogen in our systems when not organic.